Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, occurs when blood flow stops to a part of the heart causing damage to the heart muscle. It results from a biphasic ischemia/reperfusion (I/R) injury to the heart. Despite considerable effort,...
Syncrosome invites you to visit us at 2nd Annual Neuroscience Biopartnering & Investment Forum, March 27th to March 28th, In New-York, USA. The Forum will be focused on Neurodegenerative Diseases with a mix of specialist panels and company presentations. It will be the occasion for Syncrosome to...
The last january, all the Syncrosome laboratory an commercial team participated on a 2-day team building event in the French Alpes. It was an enthusiastic "scientific and sportive" experience for everyone! After different meetings to exchange on topics like: Important scientific and commercial results obtained in 2016, ...
Congestive heart failure (CHF) is a serious outcome of myocardial infarction (MI). Animal models have been used to study various aspects of CHF. Postinfarction animal models have been extensively studied because myocardial ischemia and infarction are frequent causes of CHF in humans. However, not all...
Alzheimer's disease (AD) is a progressive neuro-psychiatric disorder which is characterized by the formation of senile plaques (SPs), extracellular deposits of amyloid beta-peptides (Aβ) following intracellular neurofibrillary tangles (NFTs) of the microtubule-associated protein tau. Both cause neuronal degeneration, extensive loss of neurons and synaptic loss...
January 2017 is a great month for all the Syncrosome Laboratory and Commercial team. On Sunday 29th of January, all the team will be leaving for the French Alpes on a 2-day Team building experience. Our goal is to summarize Syncrosome’s 2016 life and events to...
Pulmonary arterial hypertension (PAH) is a rare cardiopulmonary disorder characterized by progressive obliteration of small pulmonary arterioles that leads to increased pulmonary vascular resistance. Because of impaired blood flow inpulmonary arteries, right ventricular pressure (RVSP) rises, ultimately leading toright ventricular failure and premature death. This...
To characterize the expression in skin nerves of native (n-syn) and misfolded phosphorylated (p-syn) α-synucleins in pure autonomic failure (PAF) and idiopathic Parkinson disease (IPD). The specific aims were to (1) define the importance of n-syn and p-syn as disease biomarkers and (2) ascertain differences...
Temperature sensitive anti-inflammatory Novel therapeuthic target against IBD Ulcerative colitis (UC) together with Crohn’s disease (CD), are Inflammatory bowel diseases (mouse IBD). The chronic and relapsing inflammation of all or part of the digestive tract causes severe diarrhea, pain, fatigue and weight loss. Researchers currently...