Microdialysis, a valuable tool for preclinical drug assessment and pharmacokinetic.
This approach allows to take:
- A unique Central Nervous System (CNS),
- Multiple Central Nervous System samples,
- Multiple simultaneous blood and Central Nervous System samples.
Applications:
- Measurement of extracellular concentrations of exogenous compounds
- Assessment of BBB passage
- Pharmacokinetic and distribution of given compound
- Correlation between behaviours and neurotra...