Blog's Syncrosome

In vivo pharmacology and CNS-PK for Stroke and Parkinson’s disease

Syncrosome is a preclinical CRO dedicated to In vivo pharmacology since 12 years now and with a strong competency in Efficacy and Pharmacokinetics. One of our department is dedicated to Central Nervous System and we propose a complete offer with: - In vivo efficacy models in Parkinson and Stroke - CNS-PK with Microdialysis and CSF sampling - Immunohistochemistry Sandra Robelet, Head of CNS department, will attend the 8th Annual Biomarkers Congress, 19 & 20 Feb 2013, Manchester. It will ...

In vivo Microdialysis: a valuable tool for preclinical drug assessment

As you probably know Syncrosome offers Advanced services in CNS efficacy with model in Parkinson and Stroke diseases but also in CNS-PK thanks to microdialysis and CSF sampling. Microdialysis is an in vivo technique allowing continuous sampling of molecules in brain extracellular space in the same animal. Associated to a detection technique, Microdialysis allows the monitoring of Neurotransmitter such as Dopamine, Serotonin, Nor-Adrenaline but also drug delivery in a particular brain area....