As you probably know, Syncrosome is involved in the Gastro-Intestinal field since 10 years now. Our Neurogastroenterology Department developped different models in Pharmacodynamics and Proof of efficacy :
- Emesis and Nausea
- Irritable Bowel Disease and Irritable Bowel Syndrome
- Intestinal motility
- Gastric emptying…
We implemented in vivo tests to evaluate Emesis & Nausea in ferrets and piglets and we have already evaluated numerous therapeutic classes in these 2 models for Pharmaceutical and Biotech companies . Recently, we tested Morphine and its metabolite in a ferret model to obtain new datas.
Feel free to contact us if you want to see the results and discuss about potocols and timelines for your study!
Syncrosome is an independent CRO specialized in preclinical drug evaluation. Founded in 2000 by Richard Mitry, Syncrosome offers services and an expertise in the development of Cardiovascular, Central Nervous, Respiratory and Gastrointestinal drugs to Big pharma, midsize pharma and biotechnology companies around the world. In recognition to is research, Syncrosome was recently awarded by the French Ministry with the « Credit Impôt Recherche ».